Journal of Foot and Ankle Surgery (Asia Pacific)

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VOLUME 9 , ISSUE 2 ( April-June, 2022 ) > List of Articles


Giant Cell Tumor of the Talus: A Case Report and Review of Literature

Dharampal Swami, Nitesh Gahlot, Abhay Elhence

Keywords : Case reports, Giant cell tumor, Giant cell tumor talus, Management, Outcome, Review of literature

Citation Information : Swami D, Gahlot N, Elhence A. Giant Cell Tumor of the Talus: A Case Report and Review of Literature. J Foot Ankle Surg Asia-Pacific 2022; 9 (2):92-95.

DOI: 10.5005/jp-journals-10040-1162

License: CC BY-NC 4.0

Published Online: 01-04-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Aim and objective: This study aims to describe a rare case of giant cell tumor (GCT) of the talus. Background: Giant cell tumors rarely present around bones of the foot and involvement of the talus is infrequent. In comparison to long bones, diagnosis and management of talus GCT is challenging and is sparsely reported in the literature. Case description: We report a case of GCT arising from the talus in a 19-year-old boy, presenting as non-specific foot pain for the past 2 months. The diagnosis was established by open biopsy and treated with curettage, bone grafting, and subtalar joint arthrodesis. At 6 months of follow-up, the patient had painless arthrodesis of subtalar joint with functional ankle joint and no sign of recurrence at last clinicoradiological examination. Conclusion: Diagnosis and management of GCT talus is challenging and can be treated with extended curettage with subtalar arthrodesis. Clinical significance: Presentation of GCT talus may be missed at early stages. A high index of suspicion can help in diagnosis and appropriate management.

  1. Sobti A, Agrawal P, Agrawal M. Giant cell tumor of bone - an overview. Arch Bone Jt Surg 2016;4(1):2–9.
  2. Campanacci M, Baldini N, Boriani S, et al. Giant-cell tumor of bone. J Bone Joint Surg Am 1987;69(1):106–114. DOI: 10.2106/00004623-198769010-00018.
  3. Sharma S, Wani IH, Nital G, et al. Giant cell tumor of talus: a case report. Cases J 2009;2(1):74. DOI: 10.1186/1757-1626-2-74.
  4. Biscaglia R, Bacchini P, Bertoni F. Giant cell tumor of the bones of the hand and foot. Cancer 2000;88(9):2022–2032. DOI: 10.1002/(SICI)1097-0142(20000501)88:9<2022::AID-CNCR6>3.0.CO;2-Y.
  5. Minhas MS, Khan KM, Muzzammilm M. Giant cell tumour of foot bones — 25 years experience in a tertiary care hospital. J Pak Med Assoc 2015;65(11 Suppl 3):S67–S71.
  6. Goldenberg RR, Campbell CJ, Bonfiglio M. Giant cell tumour: an analysis of 218 cases. JBJS 1970;52A(4):619–664. DOI: 10.2106/00004623-197052040-00001.
  7. Sung HW, Kuo DP, Shu WP, et al. Giant cell tumour: an analysis of 208 cases in Chinese patients. JBJS 1982;64A(5):755–761. DOI: 10.2106/00004623-198264050-00015.
  8. Malawer MM, Vance R. Giant cell tumor and aneurysmal bone cyst of the talus: clinicopathological review and two case reports. Foot Ankle 1981;1(4):235–244. DOI: 10.1177/107110078100100407.
  9. Mechlin MB, Kricun ME, Stead J, et al. Giant cell tumor of tarsal bones. Report of three cases and review of the literature. Skeletal Radiol 1984;11(4):266–270. DOI: 10.1007/BF00351351.
  10. Wold LE, Swee RG. Giant cell tumor of the small bones of the hands and feet. Semin Diagn Pathol 1984;1(3):173–184.
  11. Makashir R, Chauhan S, Kapoor R, et al. Primary tumors of small bones: a clinicopathological and radiological study. Indian J Patholmicro 1991;34(1):30–38.
  12. Dhillon MS, Singh B, Singh DP, et al. Primary bone tumors of the talus. J Am Podiatr Med Assoc 1994;84(8):379–384. DOI: 10.7547/87507315-84-8-379.
  13. Bapat MR, Narlawar RS, Pimple MK, et al. Giant cell tumour of talar body. J Postgrad Med 2000;46:110.
  14. Schoenfeld AJ, Leeson MC, Grossman JP. Fresh-frozen osteochondral allograft reconstruction of a giant cell tumor of the talus. J Foot Ankle Surg 2007;46(3):144–148. DOI: 10.1053/j.jfas.2006.10.004
  15. Mondal S, Banik R, Sarkar A, et al. Giant cell tumour of the talus: a rare case report. IOSR J Dent Med Sci, Ver. III 2015;14(2):72–74.
  16. Bhattacharyya A, Rana D, Darwani R. Giant cell tumor of the Talus: A case report and review of literature. Foot Ankle Online J 2010; 3(8):2.
  17. Mohan Kumar J, Gowda N. Giant cell tumor of talus: a case report of late presentation with extensive involvement. Foot Ankle Online J 2011;4(1):1.
  18. Young PS, Bell SW, Macduff EM, et al. Primary osseous tumors of the hindfoot: why the delay in diagnosis and should we be concerned? Clin Orthop Relat Res 2013;471(3):871–877. DOI: 10.1007/s11999-012-2570-6.
  19. Song K-S, Park CH. Giant cell tumor of the talus: 19-year follow-up of a patient. J Foot Ankle Surg 2015;54(5):958–961. DOI: 10.1053/j.jfas.2014.04.003.
  20. Bell SW, Young PS, Mahendra A. Primary bone tumours of the talus: the Scottish bone tumour registry experience. Foot Ankle Surg 2012;18(4):277–282. DOI: 10.1016/j.fas.2012.04.007.
  21. Islam MS, Ara R, Alam MT, et al. Giant cell tumour of the talus: a rare case repMed Jort. Mymensingh 2019;28(3):689–693.
  22. Galvan D, Mullins C, Dudrey E, et al. Giant cell tumor of the talus: A case reports. Radiol Case Rep. 2020;15(7):825–831. DOI: 10.1016/j.radcr.2020.03.016.
  23. Rahul KC, Sinha VP. Diagnosis and management of giant cell tumour of talus: a case report. Int J Orthop Sci 2020;6(1):246–248. DOI: 10.22271/ortho.2020.v6.i1e.1866.
  24. Carrasco CH, Murray JA. Giant cell tumours. Orthopclin North Am 1989;20:395–405.
  25. Oliveira VC, van der Heijden L, van der Geest ICM, et al. Giant cell tumours of the small bones of the hands and feet: long-term results of 30 patients and a systematic literature review. Bone Joint J 2013;95–B(6):838–845. DOI: 10.1302/0301-620X.95B6.30876.
  26. Xing R, Yang J, Kong Q, et al. Giant cell tumour of bone in the appendicular skeleton: an analysis of 276 cases. Actaorthopbelg 2013;79:731–737.
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