Journal of Foot and Ankle Surgery (Asia Pacific)

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VOLUME 10 , ISSUE 3 ( July-September, 2023 ) > List of Articles


Response of Heterogeneous Ulcers of Leg to Matrix Rhythm Therapy: A Case Series

Gurunath S Wachche, Sandeepa Bhagwat, Manisha Talpalikar, Naik Varun, Deepa Wachche

Keywords : Chronic nonhealing, Matrix Rhythm Therapy, Ulcers

Citation Information : Wachche GS, Bhagwat S, Talpalikar M, Varun N, Wachche D. Response of Heterogeneous Ulcers of Leg to Matrix Rhythm Therapy: A Case Series. J Foot Ankle Surg Asia-Pacific 2023; 10 (3):156-160.

DOI: 10.5005/jp-journals-10040-1239

License: CC BY-NC 4.0

Published Online: 07-07-2023

Copyright Statement:  Copyright © 2023; The Author(s).


Background: Matrix Rhythm Therapy (MaRhyThe©) is a recent advancement in the field of physiotherapy. It is a treatment instrument which helps in enactment and equalization of the typical physiological vibrations of the skeletal muscles and the sensory system. Objective: To describe the effect of MaRhyThe© as an adjunct in patients in heterogeneous ulcers of the leg. Design: Case series. Setting: Orthopedic and physiotherapy center in Solapur. Patients: Five cases with heterogeneous leg ulcers from a single center were recruited and were treated with MaRhyThe©, a handheld resonator by trained therapists. The cases have all received appropriate therapies, however, they failed to heal before the referral. The ulcers were measured before the start of therapy and MaRhyThe© was applied around the wound edges and the whole of the affected limb. Most cases received 60 minutes of therapy once weekly or twice weekly depending on the size of the ulcer until the absence of the wound. All cases were followed up regularly to confirm wound closure posttreatment period. Results: The median age was 50 (38–65) years. The nonhealing median period was 13 (8–16) weeks. The underlying cause of the ulcer was trauma and pressure sores. The median time to healing was 4 (2–8) weeks. In all cases, proliferation was observed following on from the first treatment session and improved with every therapy week until wound closure. Conclusion: Matrix Rhythm Therapy is a noninvasive, safe therapy and effective in treating heterogeneous ulcers of a leg in these retrospective cases.

  1. Jockenhöfer F, Gollnick H, Herberger K, et al. Aetiology, comorbidities and cofactors of chronic leg ulcers: retrospective evaluation of 1000 patients from 10 specialised dermatological wound care centers in Germany. Int Wound J 2016;13(5):821–828. DOI: 10.1111/iwj.12387
  2. Zierau UT, Martell L, Lahl W. Arteriovenous ulcers: the mixed ulcers—still the domain of arterial therapy? A case report. J Clin Stud Med Case Rep 2020;7:082. DOI: 10.24966/CSMC-8801/100082
  3. Alexiadou K, Doupis J. Management of diabetic foot ulcers. Diabetes Therapy 2012;3(1):4. DOI: 10.1007/s13300-012-0004-9
  4. Wollina U, Heinig B, Stelzner C, et al. The role of complex treatment in mixed leg ulcers—a case report of vascular, surgical, and physical therapy. Open Access. Maced J Med Sci 2018;6(1):67–70. DOI: 10.3889/oamjms.2018.023
  5. Naik V, Singh M. Effects of matrix rhythm therapy (MaRhyThe) in plantar fasciitis—an experimental study. Indian J Phys Ther Res 2019;1(2):105–109. DOI: 10.4103/ijptr.ijptr_4_19
  6. Velnar T, Bailey T, Smrkolj V. The wound healing process: an overview of the cellular and molecular mechanisms. J Int Med Res 2009;37(5):1528–1542. DOI: 10.1177/147323000903700531
  7. Hess CT. Checklist for factors affecting wound healing. Adv Skin Wound Care 2011;24(4):192. DOI: 10.1177/0022034509359125
  8. Frykberg RG, Banks J. Challenges in the treatment of chronic wounds. Adv Wound Care (New Rochelle) 2015;4(9):560–582. DOI: 10.1089/wound.2015.0635
  9. Powers JG, Higham C, Broussard K, et al. Wound healing and treating wounds: chronic wound care and management. J Am Acad Dermatol 2016;74(4):607–625. DOI: 10.1016/j.jaad.2015.08.070
  10. Jones RE, Foster DS, Longaker MT. Management of chronic wounds—2018. JAMA 2018;320(14):1481–1482. DOI: 10.1001/jama.2018.12426
  11. Han SK. Innovations and Advances in Wound Healing. Springer; 2015. p. 249–262.
  12. A Therapy Concept for the 21st Century. Dr. Randoll Institut, Gemeinnützige Gesellschaft für Matrix-Forschung und -Lehre mbH; 2020. Available from:
  13. Shrivastava S. Matrix Rhythm Therapy: a new dimension in pain management and restricted mobility—“birth injuries”. Int J Adv Res Sci Eng 2015;4(1):113–118.
  14. Leduc A, Lievens P, Dewald J. The influence of multidirectional vibrations on wound healing and regeneration of blood and lymph vessels. Lymphology 1981;14(4):179–185. PMID: 7334835.
  15. Weinheimer-Haus EM, Judex S, Ennis WJ, et al. Low-intensity vibration improves angiogenesis and wound healing in diabetic mice. PLoS One 2014;9(3):e91355. DOI: 10.1371/journal.pone.0091355
  16. Liu J, Sekiya I, Asai K, et al. Biosynthetic response of cultured articular chondrocytes to mechanical vibration. Res Exp Med (Berl) 2001;200(3):183–193. PMID: 11426670.
  17. Arashi M, Sugama J, Sanada H, et al. Vibration therapy accelerates a healing of stage I pressure ulcers in older adult patients. Adv Skin Wound Care 2010;23(7):321–327. DOI: 10.1097/01.ASW.0000383752.39220.fb
  18. Gailit J, Clark RA. Wound repair in the context of the extracellular matrix. Curr Opin Cell Biol 1994;6(5):717–725. DOI: 10.1016/0955-0674(94)90099-x
  19. Olczyk P, Mencner Ł, Komosinska-Vassev K. The role of the extracellular matrix components in cutaneous wound healing. Biomed Res Int 2014;2014:747584. DOI: 10.1155/2014/747584
  20. Randall UG, Hennig OF. Vibrations and their indication in sport-injuries. 1–8.
  21. Sarı Z, Polat MG, Özgül B, et al. The application of matrix rhythm therapy as a new clinical modality in burn physiotherapy programs. Burns 2014;40(5):909–914. DOI: 10.1016/j.burns.2013.11.009
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